Spironolactone Versus Prednisolone

Spironolactone Versus Prednisolone

Status

Phase |

Therapeutic Approach

Improving Muscle Growth & Protection

Glucocorticoids can improve strength and preserve ambulation in Duchenne, but are accompanied with unwanted side-effects. Recent preclinical data in Duchenne models showed spironolactone, a commonly used medication, increases muscle membrane stabilization with reduced negative side-effects associated with steroids.

Status

A Phase 1 trial is actively recruiting participants.

Sponsor

This program is sponsored by Nationwide Children’s Hospital.

Related Studies

ACTIVELY RECRUITING
Spironolactone Versus Prednisolone in DMD

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