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Funding Portfolio

When we began our work, the level of investment in the Duchenne research field was nearly nonexistent. Over the years, Parent Project Muscular Dystrophy (PPMD) has acted as a catalyst — funding research that is both promising and cutting edge. We were the first organization to create a drug development initiative on validated targets (Project Catalyst) to invest in the generation of boys currently affected by Duchenne. As a result of our investment, the field is now ripe with promise.

The following chart shows the various research initiatives and the awards given to those trying to develop new treatments for this generation of young men.


Make sure to:

  • Click on a research initiative in the chart to learn more
  • Click on a column heading to sort

Year Title Recipient Type Amount

2011 Validation & Preclinical studies on Drugs discovered by Utrophin promoter HTS for DMD therapy Dr. Tejvir Khurana, University of Pennsylvania Research Grant $97,869

2011 Follistatin gene therapy to improve quadriceps muscle strength Dr. Jerry Mendell, Nationwide Children's Hospital Research Grant $600,000

2011 Prevention of eccentric stress damage and contractile dysfunction by glycoprotein-based membrane strengthening in cardiac muscle Dr. Paul Janssen, Ohio State University Research Grant $50,000

2011 Optimization of renin-angiotensin-aldosterone inhibitors as a treatment for dystrophin-deficient skeletal muscles and heart Dr. Jill Rafael-Fortney, Ohio State University Research Grant $50,000

2011 Analysis of protein interactions mediated by micro-dystrophin in the mdx heart Dr. Federica Montanaro, Ohio State University Bridge Grant $50,000

2011 Tadalafil/Sildenafil Study for muscle and heart function in DMD Dr. Ron Victor, Cedars Sinai Medical Center Research Grant $753,625

2004 Project Catalyst: New Drug Development PTC Therapeutics Research Grant $2,500,000

2010 Identify novel AAV vectors for canine heart transduction by peripheral vein injection Dr. Dongsheng Duan, University of Missouri Research Grant $116,069

2010 Failed Regeneration in the Muscular Dystrophies Dr. Lee Sweeney, University of Pennsylvania Research Grant $1,050,000

2011 Failed Regeneration in the Muscular Dystrophies Dr. Stan Nelson, UCLA Research Grant $262,499

2010 Acceleron ACE-031 Dr. Jean Mah, Alberta Children's Hospital Clinical Trial Travel Funds $5,000

2010 Acceleron ACE-031 Dr. Mark Tarnopolsky, McMaster University Clinical Trial Travel Funds $5,000

2010 Acceleron ACE-031 Dr. Craig Campbell, Lawson Health Research Institute Clinical Trial Travel Funds $5,000

2010 Acceleron ACE-031 Dr. Katherine Selby, BC Children’s Hospital Clinical Trial Travel Funds $5,000

2011 AVI-4658 Dr. Jerry Mendell, Nationwide Children's Research Institute Clinical Trial Travel Funds $50,000

2011 A New Technology to Isolate Muscle Stem cells for Research Nicholas Dobes Research Grant $50,000

2011 FASEB Muscle Stem Cell Meeting Dr. Thomas Rando Meeting Support $10,000

2010 MD 2010 Conference Dr. Steve Wilton, University of Western Australia, Perth Meeting Support $5,000

2010 Antisense Oligonucleotides (AON) Therapies in Neuromuscular Disorders Dr. Edward Connor, Children's National Medical Center Meeting Support $10,000

2009 nNos as a potential therapy for DMD Nicholas Whitehead, University of Washington Research Grant $50,000

2009 Large animal model/studies Therapeutics in DMD Dr. Meg Sleeper, University of Pennsylvania Research Grant $100,000

2009 Osteopontin as a therapeutic target in DMD (anti-fibrotic) Melissa Spencer, UCLA Research Grant $50,000

2009 Improving the efficiency of antisense oligonucleotides (exon skipping) Carmen Bertoni, UCLA Research Grant $75,000

2009 Validate MRI as an outcome measure in DMD Krista Vandenborne, U. Florida Research Grant $200,000

2009 Lam III, Integrin as a potential therapy for DMD Bradley Hodges, Prothelia Research Grant $46,000

2008 Biglycan Justin Fallon, Brown University Research Grant $289,000

2009 Combined therapeutics as a treatment for DMD H. Lee Sweeney, U. Pennsylvania Research Grant $300,000

2008 6 minute walk primary outcome measure DMD PTC Therapeutics, Craig McDonald Research Grant $100,000

2010 Outcome measures for NON-AMBULATORY patients PTC Therapeutics Research Grant $50,000

2011 TREAT-NMD Advisory Committee for Therapeutics (TACT) 4th Meeting Dr. Volker Straub, University of Newcastle upon Tyne Meeting Support $25,000

2011 2nd Annual Clinical Outcome Measures in DMD Workshop Dr. Abby Bronson, Children's National Medical Center Meeting Support $1,300

2011 TREAT-NMD Advisory Committee for Therapeutics (TACT) 3rd Review Meeting Dr. Volker Straub, University of Newcastle upon Tyne Meeting Support $24,577

2011 Biomarker study in DMD Somalogic, Inc and Cincinnati Children’s Hospital Medical Center Research Grant Up to $40,900

2011 Therapeutic application of selective glucocorticoid receptor modulators in Duchenne muscular dystrophy - balancing efficacy with an improved side-effect profile Dr. Tony Huynh, Children's Research Institute Research Grant $100,000

2011 Clinical Development of SMTC1100, a Utrophin Upregulator for Duchenne Muscular Dystrophy Dr. Jon Tinsley, Summit Research Grant $250,000

2011 Review of Approved Drugs for Duchenne (RADD) Working Group Children’s National Medical Center, Nationwide Children’s Research Institute, and TREAT-NMD Research Grant $100,000

2011 Combinatorial Use of Sildenafil and Prednisone to Treat Dystrophin-Deficient Cardiac and Skeletal Muscle Dr. Stan Froehner, University of Washington Research Grant $132,322

2011 Prospective Assessment of the Prevalence of Autism and Obsessive Compulsive Disorder in the Iowa childhood onset Duchenne Becker Muscular Dystrophy Population Dr. Katherine Mathews, University of Iowa Children’s Hospital Research Grant $33,337.50

2012 Recombinant Biglycan for Treatment of Duchenne and Becker Muscular Dystrophy Joel Braunstein, Tivorsan Pharmaceuticals Research Grant $565,000

2011 Canadian DMD National Bone Health Research Initiative Dr. Leanne Ward, Children’s Hospital of Eastern Ontario Meeting Support $37,000

2012 Analysis of protein interactions mediated by micro-dystrophin in the mdx heart Dr. Federica Montanaro, Ohio State University Research Grant $52,500

2012 Pilot Project to identify genetic modifiers of Duchenne muscular dystrophy Dr. Stanley Nelson, University of California, Los Angeles Research Grant $100,000

2012 Exons 45-55 skipping with a cocktail antisense oligo Dr. Toshifumi Yokota, University of Alberta Research Grant $50,000

2012 Long-term efficacy and side effect profile of compound A, a selective glucocorticoid receptor modulator in mdx mice Dr. Kanneboyina Nagaraju, Children’s Research Institute Research Grant $50,000

2012 Development of MEMRI as an outcome measure for pre-clinical studies in the mdx mouse Dr. Volker Straub, University of Newcastle Upon Tyne Research Grant $49,003

2014 Predicting the benefit vs the side effects of corticosteroids in Duchenne muscular dystrophy Dr. Robert Griggs, University of Rochester Research Grant $78,357

2012 Magnetic Resonance Imaging as a Biomarker in Muscular Dystrophy Supplement Dr. Kristen Vandenborne, University of Florida Research Grant $59,598

2012 Clinically Meaningful Outcomes for Duchenne Muscular Dystrophy Therapeutic Trials Dr. Erik Henricson, University of California, Davis Research Grant $175,000

2012 Early treatment with Aldosterone antagonism attenuates cardiomyopathy in Duchenne MD (Epleronone Trial) Dr. Kan Hor, Cincinnati Children's Hospital Medical Center Research Grant $84,092

2012 Laminin-111 protein therapy for Duchenne Muscular Dystrophy Dr. Dean Burkin, University of Nevada, Reno Research Grant $25,000

2012 TREAT-NMD Advisory Committee for Therapeutics (TACT). 6th Meeting, Prague, Czech Republic. 27th-28th October 2012 Dr. Volker Straub, University of Newcastle Upon Tyne Meeting Grant $24,186

2012 NCH/Wellstone/OSU Myology Course Dr. Kevin Flanigan, Nationwide Children’s Hospital Meeting Grant $25,440

2012 SERCA2a gene therapy for Duchenne cardiomyopathy Dr. Donsheng Duan, University of Missouri Research Grant $280,425

2012 Preclinical investigation of tamoxifen in mdx miceas prerequisite for a clinical trial in DMD patients Dr. Urs Ruegg, University of Geneva Research Grant $164,100

2012 TREAT-NMD Advisory Committee for Therapeutics (TACT). 5th Meeting, Arlington VA, USA. 28-29 April 2012 Dr. Volker Straub, University of Newcastle upon Tyne Meeting Grant $24,355

2012 A Randomized, Double-blind, Placebo-controlled, Multiple-dose, Dose-escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Effects of HT-100 in Patients with Duchenne Muscular Dystrophy Marc Blaustein, Halo Therapeutics, LLC GIFTED $100,000
  2012 New Directions in Biology and Disease of Skeletal Muscle-New Orleans, LA Dr. Lee Sweeney, University of Pennsylvania Meeting Grant $20,000
  2010 New Directions in Biology and Disease of Skeletal Muscle-New Orleans, LA Dr. Lee Sweeney, University of Pennsylvania Meeting Grant $20,000
  2008 New Directions in Muscle Biology and Disease Meeting Dr. Lee Sweeney, University of Pennsylvania Meeting Grant $30,000
  2006 New Directions in Muscle Biology and Disease Meeting Dr. Lee Sweeney, University of Pennsylvania Meeting Grant $20,000
  2004 New Directions in Muscle Biology and Disease Meeting Dr. Lee Sweeney, University of Pennsylvania Meeting Grant $35,000
  2013 Enhancement of the muscle environment for stem cell transplantation Dr. Kathryn Wagner, Kennedy Krieger Institute Research Grant $35,000
  2013 Second annual NCH/Wellstone/OSU Myology Course Dr. Kevin Flanigan, Nationwide Children’s Hospital Meeting Grant $22,183
  2013 Magnetic Resonance Imaging as a Biomarker in Muscular Dystrophy - Supplement 2013 Dr. Krista Vandenborne, University of Florida Research Grant $17,050
  2013 Clinical Development “Superhighway”: a program to create efficient drug development in DMD Dr. Elliot Goldstein, DART Therapeutics GIFTED $300,000
  2013 TREAT-NMD Advisory Committee for Therapeutics (TACT), 7th meeting, Baltimore MD, USA, 27-28 April 2013 Dr. Volker Straub, University of Newcastle Upon Tyne Meeting Grant $15,000
  2013 Development of Novel Upper Extremity Outcome Measure in Duchenne Muscular Dystrophy Dr. Gregorij Kurillo, University of California at Davis Research Grant $50,000
  2013 Duchenne Muscular Dystrophy: iPS Cells and Therapeutic Applications Dr. Rita Perlingeiro, University of Minnesota Research Grant $220,000
  2013 Preclinical testing of procysteine for reducing dystropathology in the mdx mouse model of Duchenne Muscular Dystrophy Dr. Peter Arthur, University of Western Australia Exploratory Grant $49,998
  2013 The Eureka Institute for Translational Medicine Certificate Course Dr. Carol Gregorio, University of Arizona Investigator Grant $100,000
  2013 Early Treatment with Aldosterone Antagonism Attenuates Cardiomyopathy in Duchenne Muscular Dystrophy- 2 year extension trial Dr. Subha Raman, Cincinnati Children's Hospital Medical Center Investigator Grant $52,500
  2013 ENMC workshop 204 - Biomarkers in DMD: from the discovery to the development toward clinical application and translation in other NMDs Dr. Daniel Zollinger, ENMC Meeting Grant $5,175
  2013 microRNAs as a modifier of exon skipping efficacy: feasibility of co-delivery Dr. Erica Reeves, Reveragen Exploratory Grant $49,991
  2013 TREAT-NMD Advisory Committee for Therapeutics (TACT) 8th Meeting, Newcastle, UK, 1-3 November 2013 Dr. Volker Straub, University of Newcastle Upon Tyne Meeting Grant $12,000

2014 Single AON-induced multiple exon skipping in the mdx(Cv5) mouse model Dr. Judith van Deutekom, Prosensa Research Grant $200,000

2014 Aptamer-based serum biomarker profiling in DMD longitudinal samples Dr. Annemieke Aartsma-Rus, LUMC Research Grant $49,300

2014 TREAT-NMD Advisory Committee for Therapeutics (TACT), 9th meeting, Berlin, Germany, 9-10 May 2014 Dr. Volker Straub, University of Newcastle upon Tyne Meeting Grant $7,000
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